CBD AND ANXIETY A POSSIBLE NATURAL REMEDY?

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ACCUMULATED EVIDENCE INDICATES THAT CANNABIDIOL (CBD), A MAJOR NONPSYCHOTROPIC AND NON-ADDICTIVE COMPONENT OF THE CANNABIS SATIVA PLANT, REVERSES ANXIETY-LIKE BEHAVIOR. 

Having to face an important and / or novel situation, face a fundamentally important work day, strive to get through your university exams, take care of your home and your family, have a date, go through a breakup, meet with your superior or go to a job interview, deal with situations that have caused us stress in the past...

It is common for many people when they find themselves in these series of circumstances to begin to feel fear, overwhelmed, shortness of breath, nausea and stomach pain. These discomforts can be linked to excess stress that causes anxiety symptoms. According to preclinical trials, CBD has potential as a natural remedy to reduce such symptoms.

 

¿WHAT IS ANXIETY? 

The term anxiety can refer not only to a more chronic disorder but also to its symptoms that can appear acutely. It is a natural adaptive mechanism that puts us on alert to compromised situations, being adequate to prevent dangerous situations and keep us focused in circumstances where we must give 100%.

Problems arise when there is excess stress and there are not enough tools to handle it, therefore people can feel overwhelmed, overwhelmed and with a sense of resignation in a situation that exceeds their own capacities.

All this can be worsened in people who have experienced traumatic experiences of different degrees, so the symptoms can be associated with similar experiences or simply with stimuli that are associated with their memory, and can cause panic attacks that usually represent another traumatic event, thus expanding the chain and leading the person to a disabling situation.

The subject suffering from anxiety may feel especially vulnerable, defenseless and a deterioration of psychosocial and physiological functioning may occur.

 

Symptoms related to anxiety episodes are:

  1. Palpitations or tachycardia
  2. Feeling short of breath and overwhelmed, with rapid breathing.
  3. Feeling of tightness in the chest.
  4. Fear or panic Literally feeling in danger.
  5. Sweating or chills.
  6. Tremors.
  7. Nausea or abdominal discomfort.
  8. Dizziness or even fainting.

If the anxiety is persistent and intense, it can prevent the person from carrying out a normal day-to-day life.

HOW CAN NATURE SCIENCE CBD HELP YOU TO TREAT ANXIETY?

¿WHAT IS CBD? PROPERTIES AND BENEFITS OF CBD.

CBD (Cannabidiol) is the second most abundant cannabinoid among the phytocannabinoids that can be found in Cannabis Sativa L plants. Unlike many other cannabinoids, CBD is not psychotropic and has a different beneficial and therapeutic profile than other cannabinoids psychoactive, recognized by the WHO.

WHY IS CBD GOOD FOR ANXIETY?

One of the properties of CBD is anxiolytic, it acts in our body through the receptors of the endocannabinoid system, regulating the activity of the amygdala and the insula, whose activity is related to the emotions and symptoms linked to anxiety disorders and the stress, such as fear, disgust or sadness, but also love and happiness. For this reason, its role as a regulator and modulator of the activity of these brain structures is important.

Stress by definition is not always negative, since it produces hormones such as adrenaline, dopamine, or serotonin influencing the energy of the person, increasing their vitality and confidence to face a problem. However, when stress is continued, or cannot be managed, the body generates different hormones such as cortisol, producing a feeling of exhaustion and irritability or even lack of motivation. CBD stimulates specific receptors capable of modulating serotonergic and dopaminergic activity to promote a physiological balance whose effect on a psychological level is anxiolytic and antidepressant.

EVIDENCE OF THE BENEFITS OF CBD FOR ANXIETY

Existing preclinical evidence strongly supports CBD's potential as a treatment for anxiety disorders. This is because CBD exhibits a range of effective properties for some symptoms, including its anxiolytic, antipsychotic, panolytic and anti-compulsive actions, a decrease in fear and prevention of long-term anxiety effects due to stress.

These preclinical studies have shown that CBD interacts with the receptors that regulate behaviors related to fear and anxiety, specifically the cannabinoid receptor type 1 (CB1), the serotonin receptor 5-HT1A and the potential of a transient receptor. (TRP) vanilloid type 1 (TRPV1).

CBD, administered systematically on a regular basis, reduced the acute increases in heart rate and blood pressure induced by stress, as well as the delayed anxiogenic effects of stress (Those that occur 24 hours after the stress-inducing event). CBD has also been shown to improve the extinction of fear responses in addition to blocking the re-consolidation of aversive memories.

In summary, it can be seen how CBD is a complete and comprehensive therapeutic tool, capable of acting both on a physical, psychological and emotional level, representing one of the most appropriate treatments for anxiety and stress disorders.

HOW TO USE CBD TO TREAT ANXIETY

CBD, unlike other substances that have more direct action (stimulate or inhibit), is capable of modulating and indirectly enhancing the endocannabinoid system, so that all the physiological processes necessary to restore the homeostasis (balance) of each body.

All people have a different body that is characterized by a unique and personal balance, therefore each person will have their specific ways to deal with different problematic situations such as anxiety, requiring the most personalized treatment possible.

For these reasons, it is difficult to establish an effective amount of CBD for anxiety in general, since it is necessary to find the most suitable dosage for each person. In addition, anxiety can be triggered by very personal causes and each person tends to resort to very different therapies and tools, making each therapeutic journey very specific.

This is why the different clinical studies that have been carried out and are being carried out usually use a dosage that can vary from 30 mg to 800 mg daily, in addition to using different routes of administration.

 

ROUTES OF ADMINISTRATION

Inhaled route: the effect is immediate and maximum from the beginning, therefore the inhaled form can help to relieve acute episodes of anxiety and / or panic or feelings of distress.

Sublingual route: it is the most recommended way for a medium / long-term treatment and to provide relief in more chronic situations such as a continuous anxious state

Topical route: it can provide relief in areas of the body that tend to tense during anxiety episodes such as the cervical and pectorals.

 

CBD TO TREAT ANXIETY AND INSOMNIA

Anxiety can affect other factors in our life such as sleep, leading to insomnia. CBD treatment for anxiety is recognized and according to studies, if the dosage is stable in the long term it has therapeutic potential to improve sleep.  

CAN I CAUSE A POISONING FROM ABUSE OF CBD? WHAT HAPPENS IF I USE HIGH DOSES OF CBD?

CBD has been found to have a bell-shaped response curve, meaning that higher doses are not necessarily more effective, if not quite the opposite. So it is essential to find the appropriate dose for the subject. To do this, it is recommended to start with a low dose and gradually increase until the effects appear.

The possible adverse effects of CBD according to the Canna Foundation are: "tiredness, drowsiness, dry mouth, dizziness and decreased appetite" that decrease when reducing the dose of CBD or suspending the administration.

¿WHAT ABOUT THC?

Due to its psychoactivity, THC can cause an anxiogenic effect, that is, it produces anxiety, especially in people who have a propensity, therefore its use is not recommended in people who suffer from anxiety episodes.

HAS CBD BEEN SCIENTIFICALLY PROVEN TO HELP WITH ANXIETY AND DEPRESSION?

The simple answer is: No, there are preclinical trials, such as those cited above, that show it is effective, but more research is needed. The range of conditions for which CBD has been evaluated is diverse, consistent with its neuroprotective, antiepileptic, anxiolytic, antipsychotic, analgesic, and anti-inflammatory properties.

Much more research and clinical studies are required to evaluate CBD as a possible treatment for anxiety and depression. That does not mean that it would not help, but properly controlled clinical trials are necessary to support the indication of CBD to treat anxiety or depression.

Thanks to preclinical results and other research around the world, the regulatory and bureaucratic framework increases its acceptance of the use of cannabinoids as a therapeutic alternative. In countries like the USA, Sweden or Canada, CBD is allowed for ingested use.

Still, much remains to be learned about the complex endocannabinoid system and how it interacts with the different cannabinoids. The key to these advances is the destigmatization of the cannabis plant and the promotion of clinical trials.

 

 

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